Knox Nonstop Request a nonstop
A widebody jet parked at a jet bridge on a floodlit apron at night while ground crews load cargo

Not served from TYS · yet

Where Knoxville can't fly nonstop.

People in East Tennessee search for these cities all the time, and TYS doesn't fly to any of them. Here is the best one-stop for each, the drive when it makes sense, and a button to tell the airlines you want it.

Photo: Pexels

Short answer

As of October 19, 2026, Knoxville (TYS) has no nonstop to Pittsburgh, San Diego, Seattle, Los Angeles, Cancún, Myrtle Beach, New Orleans, Pensacola. Each is reachable with one stop on a single airline, for example Pittsburgh via Charlotte (American); San Diego via Nashville (Southwest); Seattle via Nashville (Southwest); Los Angeles via Nashville (Southwest).

Missing routes

The gap, in numbers

8searched-for cities with no TYS nonstop.
3West Coast cities on the list, each one stop from TYS.
8h 34mdrive from TYS to Myrtle Beach airport.
2019the last scheduled Knoxville to Pittsburgh nonstop we found (Allegiant, seasonal).

Finder

Pick a city. See your best way there.

Every option is a real Knoxville nonstop to a hub plus a real nonstop on the same airline from that hub. Then tell the airlines you want the nonstop.

No nonstop yet: best connections

22 one-stop options to Pittsburgh on a single airline (straight line from Knoxville: 382 mi).

9h 43mDrive, downtown Pittsburgh to TYS · 508 road miles (OSRM, no traffic)
2019Allegiant flew a seasonal Pittsburgh route, twice a week, starting May 17, 2019. We found no scheduled nonstop since.

There is an active campaign for a PIT to TYS nonstop at flypittys.com.

  1. 1Via Charlotte CLT

    American

    176 mi + 367 mi = 543 mi · 42% longer than a straight line

  2. 2Via Washington IAD

    United

    419 mi + 182 mi = 601 mi · 57% longer than a straight line

  3. 3Via Nashville BNA

    Southwest

    152 mi + 461 mi = 613 mi · 60% longer than a straight line

  4. 4Via Washington DCA

    American

    436 mi + 204 mi = 640 mi · 68% longer than a straight line

  5. 5Via Detroit DTW

    Delta

    444 mi + 201 mi = 645 mi · 69% longer than a straight line

  6. 6Via Baltimore/Washington BWI

    Southwest

    464 mi + 210 mi = 674 mi · 76% longer than a straight line

A one-stop option means Knoxville has a nonstop to the hub and the same airline flies nonstop from that hub to the destination, so it can be sold on one ticket. Hub routes come from each hub's published destination list (Wikipedia, checked October 19, 2026); Knoxville routes from our verified list. Ranked by total great-circle miles, a fair proxy for time in the air. Check the airline for actual schedules and connection times.

Map

The routes Knoxville is missing

Pittsburgh?San Diego?Seattle?Los Angeles?Cancún?Myrtle Beach?New Orleans?Pensacola? TYS

Demand

Ranked by what people search for.

The demand score sums how often and how high each city appears in Google and Bing autocomplete for "flights from knoxville to …" and "… to knoxville", from our crawl on October 19, 2026. It is a relative signal, not a passenger count, and autocomplete is localized, so treat it as directional.

Cities without a Knoxville nonstop, search demand and best one-stop option
CitySearch demand scoreShortest one-stopOne-stop optionsRequest
Pittsburgh PIT97.9Via Charlotte American
543 mi total
22
San Diego SAN66.2Via Nashville Southwest
1,899 mi total
20
Seattle SEA66Via Nashville Southwest
2,126 mi total
18
Los Angeles LAX54.9Via Nashville Southwest
1,945 mi total
21
Cancún CUN31.1Via Atlanta Delta
1,035 mi total
18
Myrtle Beach MYR16Via Charlotte American
332 mi total
17
New Orleans MSY15.2Via Atlanta Delta
577 mi total
22
Pensacola PNS11Via Atlanta Delta
424 mi total
15

Request a nonstop

Where should Knoxville fly next?

Name the city. Every request is counted and the leaderboard goes to the airport's air-service team, the people who pitch new routes to airlines.

… requests from TYS so far

  1. Loading the leaderboard…
Mostly for
Round trips a year you'd fly it

Your email is optional and never shown. City counts are public.

Downtown Pittsburgh lit up at blue hour from Mount Washington, with Point State Park, the rivers and the Fort Pitt Bridge below
No nonstopPittsburghAllegiant flew it seasonally in 2019.
Seattle skyline from Kerry Park with the Space Needle and snow-capped Mount Rainier at sunset
No nonstopSeattleOne stop via many hubs.
Griffith Observatory on Mount Hollywood silhouetted against the hazy downtown Los Angeles skyline
No nonstopLos AngelesOne stop via many hubs.
The SkyWheel Ferris wheel on the beach at Myrtle Beach, South Carolina, with oceanfront hotels and a fishing pier in the distance
No nonstopMyrtle BeachDrive or connect.
St. Louis Cathedral and the Andrew Jackson statue in Jackson Square, New Orleans' French Quarter
No nonstopNew OrleansOne stop via a hub.

Questions

Is there a nonstop flight from Knoxville to Pittsburgh?
No. The best same-airline one-stop by distance is via Charlotte on American. The drive from downtown Pittsburgh to TYS is about 9h 43m (508 miles). Allegiant flew the route seasonally in 2019.
Is there a nonstop from Knoxville to Myrtle Beach?
No. The drive from TYS to Myrtle Beach airport is about 8h 34m by OSRM. One-stop options include Charlotte (American), Atlanta (Delta), Nashville (Southwest).
Is there a nonstop from Knoxville to Seattle or Los Angeles?
No. Both need one stop; the shortest same-airline routings are via Nashville for Seattle and Nashville for Los Angeles.
Is there a nonstop from Knoxville to Pensacola?
No. Allegiant flies to nearby Destin/Fort Walton Beach (VPS), about 1h 18m by road from Pensacola Beach.
Is there a nonstop from Knoxville to Cancún?
No. Knoxville has no international flights. See connections to the world for every one-stop option.
How do I ask for a new route from Knoxville?
Use the request form on this page. Every request is counted, and the leaderboard is shared with the airport's air-service team.

Sources

  1. McGhee Tyson Airport: nonstop flights (airport page, 35 cities)
  2. McGhee Tyson Airport: Allegiant announces Pittsburgh nonstop, beginning May 17, 2019 (Feb 12, 2019)
  3. McGhee Tyson Airport: new nonstops, seasonal, twice weekly (May 17, 2019)
  4. OSRM routing on OpenStreetMap data (drive times, no traffic)
  5. U.S. State Department: Mexico international travel information
  6. flypittys.com: the Pittsburgh to Knoxville nonstop campaign
  7. Wikipedia: Charlotte Douglas International Airport, airlines and destinations
  8. Wikipedia: Washington Dulles International Airport, airlines and destinations
  9. Wikipedia: Nashville International Airport, airlines and destinations
  10. Wikipedia: Ronald Reagan Washington National Airport, airlines and destinations
  11. Wikipedia: Detroit Metropolitan Wayne County Airport, airlines and destinations
  12. Wikipedia: Baltimore/Washington International Thurgood Marshall Airport, airlines and destinations
  13. Wikipedia: Hartsfield Jackson Atlanta International Airport, airlines and destinations
  14. Wikipedia: Philadelphia International Airport, airlines and destinations
  15. Wikipedia: Chicago O'Hare International Airport, airlines and destinations
  16. Wikipedia: Newark Liberty International Airport, airlines and destinations
  17. Wikipedia: LaGuardia Airport, airlines and destinations
  18. Wikipedia: Orlando International Airport, airlines and destinations
  19. Wikipedia: Tampa International Airport, airlines and destinations
  20. Wikipedia: Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field, airlines and destinations
  21. Wikipedia: Miami International Airport, airlines and destinations
  22. Wikipedia: Dallas Love Field, airlines and destinations
  23. Wikipedia: Dallas Fort Worth International Airport, airlines and destinations
  24. Wikipedia: George Bush Intercontinental Airport, airlines and destinations
  25. Wikipedia: Austin Bergstrom International Airport, airlines and destinations
  26. Wikipedia: Denver International Airport, airlines and destinations